Rabbit anti-TBK1 Antibody
Catalog #
TBK1
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 675 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
TBK1 is a member of the I-kappa-B kinase (IKK) family that plays a role in embryonic development and in the innate immune response. In response to viral infection, TBK1 activity induces transcription of genes such as IFN-gamma inducible protein (ip10), and interferon beta (ifnb). TBK1 is also implicated in the NF-kappa-B activation pathway which involves phosphorylation of I-kappaB proteins and the release and translocation of the NF-kappa-B complex to the nucleus.
Alternate Names
FTDALS4; IIAE8; NAK; NF-kappa-B-activating kinase; NF-kB-activating kinase; serine/threonine-protein kinase TBK1; T2K; TANK-binding kinase 1
Applications