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Primary Antibodies  

Rabbit anti-PARD3 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

PARD3

Reactivity:

Human

,

Mouse

Applications:

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 1306 and 1356

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Presumed Reactivity

Rat

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

Partitioning defective 3 homolog (Par3) is an adapter protein involved in asymmetrical cell division and cell polarization processes. It seems to play a central role in the formation of epithelial tight junctions and targets the phosphatase PTEN to cell junctions (By similarity). Par3 association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Par3 is required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TEW0].

56288

PARD3

par-3 family cell polarity regulator

Q8TEW0

Partitioning defective 3 homolog

Alternate Names

ASIP; atypical PKC isotype-specific interacting protein; Atypical PKC isotype-specific-interacting protein; Ba; Zbazooka; CTCL tumor antigen se2-5; PAR3; PAR-3; par-3 family cell polarity regulator alpha; par-3 partitioning defective 3 homolog; PAR3alpha; PAR3-alpha; PARD-3; PARD3A; partitioning defective 3 homolog; PPP1R118; protein phosphatase 1, regulatory subunit 118; SE2-5L16; SE2-5LT1; SE2-5T2

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).