/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-PVRL1/NECTIN1 Recombinant Monoclonal Antibody [BLR274L]
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Primary Antibodies  

Rabbit anti-PVRL1/NECTIN1 Recombinant Monoclonal Antibody [BLR274L]

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

PVRL1/NECTIN1

Reactivity:

Human

Applications:

Flow Cyt

,

IP

,

WB

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR274L

Format:

Whole IgG

Immunogen:

residues 31-331 (ECD)

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (10 blots)

20 µl (2 blots)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


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Additional Product Information

PVRL1/NECTIN1 (aka CD111) is an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily. It acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2) and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells [taken from NCBI Entrez Gene (Gene ID: 5818)].

5818

NECTIN1

nectin cell adhesion molecule 1

Q15223

Nectin-1

Alternate Names

CD antigen CD111;CD111;CLPED1;ectodermal dysplasia 4 (Margarita Island type);ED4;herpes simplex virus type 1 sensitivity;herpes virus entry mediator C;Herpesvirus entry mediator C;herpesvirus Ig-like receptor;HIgR;HV1S;HVEC;nectin 1;Nectin cell adhesion molecule 1;nectin-1;OFC7;poliovirus receptor-like 1;poliovirus receptor-related 1 (herpesvirus entry mediator C);poliovirus receptor-related protein 1;PRR;PRR1;PVRL1;PVRR;PVRR1;SK-12

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.