Rabbit anti-CAV1 Antibody, Affinity Purified
Catalog #
CAV1
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Cat,
Mouse,
Horse,
Sheep,
Pig,
Rabbit,
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
CAV1 acts as a scaffolding protein within caveolar membranes and forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. CAV1 also mediates the recruitment of CAVIN proteins to the caveolae and interacts directly with G-protein alpha subunits and can functionally regulate their activity. CAV1 is also thought to be involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation, as its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q03135].
Alternate Names
BSCL3; caveolin 1, caveolae protein, 22kDa; caveolin-1; cell growth-inhibiting protein 32; CGL3; LCCNS; MSTP085; PPH3; VIP21
Applications