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Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E]
Bethyl Laboratories®
Catalog #
Validated
Target:
Granzyme B
Reactivity:
Human
Applications:
ICC
,IHC
,IHC-IF
,mIF
,WB
Platforms:
COMET™
,PhenoImager™ HT
Host:
Rabbit
Clonality:
Recombinant Monoclonal
Clone:
BLR022E
Format:
Whole IgG
Immunogen:
residues 19-247 (mature protein)
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Purified
100 µl (50+ tests)
10 µl (5+ tests)
100 µg (BSA-Free)
Product Details
Specifications
Verified Reactivity
Human
Antigen Species
Human
Concentration
50 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
Request Formulation Change
Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Request Formulation Change
Additional Product Information
Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]
Alternate Names
C11; cathepsin G-like 1; CCPI; CGL1; CGL-1; CSPB; CSP-B; CTLA1; CTLA-1; CTSGL1; cytotoxic serine protease B; cytotoxic T-lymphocyte proteinase 2; fragmentin 2; Fragmentin-2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); Granzyme-2; HLP; human lymphocyte protein; Lymphocyte protease; SECT; T-cell serine protease 1-3E
Applications
