Rabbit anti-BMI1 Recombinant Monoclonal Antibody [BLR119H]
Catalog #
BMI1
Human
,Mouse
Flow Cyt
,ICC
,IHC
,IP
,WB
Rabbit
Recombinant Monoclonal
BLR119H
Whole IgG
between 250 and 300
IgG
Unconjugated
Purified
Product Details
Human,
Mouse
Human
2 - 8 °C
1 year from date of receipt
BMI1 (B lymphoma Mo-MLV insertion region 1 homolog) is a core component of the polycomb group (PcG) multiprotein PRC1 complex which plays an important role in transcriptional repression of gene expression during development. BMI1 association with RING protein 1B is important to the E3 ligase activity of RING1B in the PRC1 complex. BMI1 is an oncogene whose overexpression is associated with many types of human tumors and is a stem-cell marker and regulator of stem cell self-renewal.
Alternate Names
B lymphoma Mo-MLV insertion region 1 homolog; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; PCGF4; polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group RING finger protein 4; ring finger protein 51; RNF51
Applications