Rabbit anti-4-1BBL/CD137L/TNFSF9 Recombinant Monoclonal Antibody [BLR148J]
Catalog #
4-1BBL/CD137L/TNFSF9
Human
Flow Cyt
,WB
Rabbit
Recombinant Monoclonal
BLR148J
Whole IgG
residues 71-254 (ECD)
IgG
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
4-1BBL (aka CD137L or TNFSF9) is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. 4-1BBL and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells; they are also involved in promoting T lymphocyte proliferation. 4-1BBL has been shown to be required for the optimal CD8 responses in CD8 T cells. 4-1BBL is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. [taken from NCBI Entrez Gene (Gene ID: 8744)].
Alternate Names
4-1BB ligand; 4-1BBL; 4-1BB-L; CD137L; homolog of mouse 4-1BB-L; receptor 4-1BB ligand; TNLG5A; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9
Applications
