NEW!
Rabbit anti-MSH2 IHC Antibody
Bethyl Laboratories®
Catalog #
Validated
Target:
MSH2
Reactivity:
Human
,Mouse
Applications:
IHC
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 875 and C-term
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)
10 µl (5+ slides)
Product Details
Specifications
Verified Reactivity
Human,
Mouse
Presumed Reactivity
Guinea_pig,
Monkey,
Pig
Antigen Species
Human
Concentration
250 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Additional Product Information
MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC).
Alternate Names
COCA1; DNA mismatch repair protein Msh2; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; mutS homolog 2, colon cancer, nonpolyposis type 1; MutS protein homolog 2
Applications
