Rabbit anti-NCAM-1/CD56 Recombinant Monoclonal Antibody [BLR152J]
Catalog #
NCAM-1/CD56
Human
ICC
,IHC
,WB
COMET™
Rabbit
Recombinant Monoclonal
BLR152J
Whole IgG
residues 20-318 (ECD)
IgG
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Phosphate Buffered Saline (PBS) containing 0.2% BSA and 0.09% Sodium Azide
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Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
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NCAM1, is a cell adhesion protein of the immunoglobulin superfamily that is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. It plays a role in the development of the nervous system by regulating neurogenesis, neurite outgrowth, and cell migration. NCAM1 is also involved in the expansion of T lymphocytes, B lymphocytes and natural killer (NK) cells which play an important role in immune surveillance. One prominent isoform NCAM1, known as cell surface molecule CD56, plays a role in several myeloproliferative disorders such as acute myeloid leukemia and differential expression of this gene is associated with differential disease progression. For example, increased expression of CD56 is correlated with lower survival in acute myeloid leukemia patients. [taken from NCBI Entrez Gene (Gene ID: 4684)].
Alternate Names
antigen recognized by monoclonal antibody 5.1H11; CD antigen CD56; CD56; MSK39; NCAM; N-CAM-1; NCAM-1; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM
Applications
