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Rabbit anti-TKS4 Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
TKS4
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 600 and 650
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (200 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

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Product Details

Specifications
Verified Reactivity
Human
Antigen Species
Human
Stock Concentration
40 µg/ml
200 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to TKS4 immobilized on solid support.

The epitope recognized by A303-437A-T maps to a region between residue 600 and 650 of human Tyrosine Kinase Substrate with Four SH3 Domains using the numbering given in entry NP_001017995.1 (GeneID 285590).

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Gene & Protein Information

TKS4 (tyrosine kinase substrate with four SH4 domains), also known as SH3 and PX domain-containing protein 2B (SH3PXD2B), is an adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. TKS4 binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. TKS4 plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ A1X283].

285590

SH3PXD2B

SH3 and PX domains 2B

A1X283

SH3 and PX domain-containing protein 2B

Alternate Names

adapter protein HOFI, adaptor protein HOFI, factor for adipocyte differentiation 49, FAD49, FTHS, HOFI, KIAA1295, SH3 and PX domain-containing protein 2B, TKS4, TSK4, tyrosine kinase substrate with four SH3 domains

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.