/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-SYK Antibody
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Primary Antibodies  

Rabbit anti-SYK Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

SYK

Reactivity:

Human

Applications:

IHC

,

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 250 and 300

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

SYK (spleen tyrosine kinase) is a ubiquitously expressed tyrosine kinase that functions in mediating B and T-cell receptor signaling and is also important to various aspects of leukocyte function that involve cytoskeleton remodeling. In mediating hematopoietic cell signaling, SYK is a substrate of src family kinase activity and is a key-regulator of Akt kinase activity. SYK has also been found to be highly expressed in the mammary gland and has been shown to inhibit tumor growth and metastasis. Invasive breast tumor cell lines have been shown to exhibit reduced or absent levels of SYK, further implicating a role in tumorigenesis and metastasis.

6850

SYK

spleen associated tyrosine kinase

P43405

Tyrosine-protein kinase SYK

Alternate Names

p72-Syk; spleen tyrosine kinase; tyrosine-protein kinase SYK

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.