Rabbit anti-BLM Antibody
Catalog #
BLM
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 1375 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Mouse
2 - 8 °C
1 year from date of receipt
Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex.
Alternate Names
Bloom syndrome homolog; Bloom syndrome protein homolog; Bloom syndrome, RecQ helicase-like; mBLM; recQ helicase homolog
Applications