Rabbit anti-beta Catenin Recombinant Monoclonal Antibody [BLR086G]
Catalog #
beta Catenin
Human
,Mouse
Flow Cyt
,ICC
,IHC
,IHC-IF
,IP
,WB
COMET™
,PhenoImager™ HT
Rabbit
Recombinant Monoclonal
BLR086G
Whole IgG
Between 731 and C-terminus
IgG
Unconjugated
Purified
Product Details
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
Request Formulation Change
Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Request Formulation Change
Recombinant antibody was purified from cell culture supernatant.
Immunogen was a peptide representing a region between residue 725 and 775 of human catenin beta 1 using the numbering given in entry NP_001895.1 (Gene ID 1499).
beta Catenin plays an integral role in the Wnt signaling pathway and is critical to morphogenic signaling and body axis specification. Beta Catenin exists in complexes with cadherins, transmembrane proteins that mediate cell adhesion. When Wnt-signaling proteins bind their receptors, beta Catenin is stabilized and accumulates in the cell. Translocation of stabilized beta Catenin allows its association with transcription factors and the activation of specific gene expression.
Alternate Names
armadillo; Beta-catenin; catenin (cadherin-associated protein), beta 1, 88kDa; catenin beta-1; CTNNB; EVR7; MRD19
Applications