Developing Effective Therapeutics for Difficult-to-Treat Cancers

Recent years have introduced a variety of novel, targeted therapies for both hematopoietic and solid tumors. This includes monoclonal antibody therapies, CAR-T cells, bispecific antibodies, vaccines, and combination immunotherapies based on checkpoint blockade. Despite these therapeutic advances, some cancers remain extremely difficult to treat. In this eBook, we highlight some hard-to-treat cancer types including breast cancer, pancreatic cancer, and cervical cancer, and recent research into the development of therapies to advance treatment of these cancers. This includes biomarker identification in breast cancer and the development of CAR-T cells to treat glioma.