/ ANTIGEN PROTEINS / Human ApoE
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ANTIGEN PROTEINS  

Human ApoE

bethyl
Bethyl Laboratories

Catalog #

Target:

ApoE

Conjugate:

Unconjugated

Purity:

Purified

0.1 mg

0.5 mg

$345.00 $1,397.00
Qty:
Bulk Request

Product Details

Specifications
Concentration
900 µg/ml
Storage

Store at -20 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

20 mM Tris-HCl, 0.15 mM NaCl, 0.5 mM EDTA, 0.02% NaN3, pH 7.4


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Country of Origin

USA

Additional Product Information

Apo E contains 299 amino acid residues. It is a 34-37 kDa glycosylated protein (Rall et al., 1983). Apo E is involved with triglyceride, phospholipid, cholesteryl ester, and cholesterol transport in and out of cells and is a ligand for LDL receptors. Apo E has also been implicated in immune and nerve degeneration. It has been found to suppress lymphocyte proliferation. Late-onset familial and sporadic Alzheimer disease patients have been found to have a higher occurrence of one of the three common Apo E isoforms, Apo E4. The Apo E4 isoform has been detected in senile plaques and neurofibrillary tangles of Alzheimer disease patients. Apo E4 is associated with rapid chylomicron-remnant clearance and increased total cholesterol levels.

348

APOE

apolipoprotein E

P02649

Apolipoprotein E

Alternate Names

AD2; APO-E; ApoE4; apolipoprotein E; apolipoprotein E3; LDLCQ5; LPG