Rabbit anti-TSC2 Antibody
Catalog #
TSC2
Human
IP
Rabbit
Polyclonal
Whole IgG
between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Rat
Human
2 - 8 °C
1 year from date of receipt
Tuberous sclerosis 2 protein (TSC2) forms a heterodimer with TSC1 to integrate cellular growth and stress signals. Defects in the TSC1 and TSC2 gene are responsible for the genetic disorder tuberous sclerosis. The TSC1/TSC2 complex functions in the mTOR pathway by negatively regulating mTOR activity via the small GTP-binding protein Rheb. TSC2 also been shown to interact with FOXO1 transcription factor.
Alternate Names
LAM; PPP1R160; protein phosphatase 1, regulatory subunit 160; TSC4; tuberin; tuberous sclerosis 2 protein
Applications