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Rabbit anti-PMVK Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
PMVK
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 142 and 192
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (10 blots)

20 µl (2 blots)

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Product Details

Specifications
Verified Reactivity
Mouse, Human
Presumed Reactivity
Bovine
Antigen Species
Human
Stock Concentration
400 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to PMVK immobilized on solid support.

The epitope recognized by A305-576A-T maps to a region between residue 142 to 192 of human Phosphomevalonate kinase using the numbering given in entry Q15126.3 (GeneID 10654).

Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

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Gene & Protein Information

PMVK is a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. PMVK protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis [taken from NCBI Entrez Gene (Gene ID: 10654)].

10654

PMVK

phosphomevalonate kinase

Q15126

Phosphomevalonate kinase

Alternate Names

hPMK, HUMPMKI, phosphomevalonate kinase, PMK, PMKA, PMKASE, POROK1, testis tissue sperm-binding protein Li 95mP

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-20% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-20% SDS-PAGE.