Rabbit anti-ASPM IHC Antibody Affinity Purified

Product Details
Specifications
The epitope recognized by IHC-00058 maps to a region between residue 3425 and the C-terminus (residue 3477) of human ASP (Abnormal Spindle)-like, Microcephaly Associated using the numbering given in entry NP_060606.2 (GeneID 259266). Antibody was affinity purified using an epitope specific to ASPM immobilized on solid support.
The epitope recognized by IHC-00058-T maps to a region between residue 3425 and the C-terminus (residue 3477) of human ASP (Abnormal Spindle)-like, Microcephaly Associated using the numbering given in entry NP_060606.2 (GeneID 259266).
Additional Product Information
ASPM (abnormal spindle-like microcephaly associated) is also known as MCPH5 (autosomal recessive primary microcephaly 5). Defects in ASPM are the cause of microcephaly primary type 5 or microcephaly vera, an autosomal recessive disease characterized by reduced head circumference, small cerebral cortex, and reduced brain weight. At the cellular level, MCPH5 is important to mitotic spindle function and may play a preferential role in prenatal neurogenesis.
Alternate Names
Abnormal spindle protein homolog; abnormal spindle-like microcephaly-associated protein; ASP; asp (abnormal spindle) homolog, microcephaly associated; Asp homolog; Calmbp1; MCPH5
Applications
Formaldehyde-fixed cells: 1:100 - 1:500:
Permeabilization with Triton-X 100 is recommended.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.