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Rabbit anti-BORG5 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

BORG5

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 150 and 200

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

BORG5 (binder of Rho GTPases 5) is part of a family of proteins that function as negative regulators of CDC42 Rho GTPase signaling. The Borg family of proteins are also known as CEPs (Cdc effector proteins) and have been shown to act downstream of Cdc42 to influence the assembly of actin filaments and changes in cell shape. BORG5 plays a role in mannose receptor-mediated phagocytosis of unopsonized Pneumocystis organisms by alveolar macrophages.

11135

CDC42EP1

CDC42 effector protein 1

Q00587

Cdc42 effector protein 1

Alternate Names

55 kDa bone marrow stromal/endothelial cell protein; binder of Rho GTPases 5; BORG5; CDC42 effector protein (Rho GTPase binding) 1; cdc42 effector protein 1; CEP1; MSE55; serum constituent protein; serum protein MSE55

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.