Bethyl Laboratories® Rabbit anti-CASC5 IHC Antibody, Affinity Purified - 100 µl (50+ slides)
Catalog #
CASC5
Human
IHC
Rabbit
Polyclonal
Whole IgG
Between 300 and 350
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Monkey
Human
2 - 8 °C
1 year from date of receipt
USA
Cancer susceptibility candidate gene 5 protein (CASC5) is predominantly expressed in testis and widely expressed in various human tumor cell lines and primary tumors from various tissues and organs. CASC5 is most frequently expressed in lung cancer and has been identified as a fusion-partner of the mixed lineage leukemia (MLL) gene, a gene often activated by chromosomal translocation in leukemias. CASC5 has also been identified as a component of the Mis12 kinetochore complex that is required for proper chromosome segregation.
Alternate Names
AF15Q14; ALL1-fused gene from chromosome 15q14 protein; Blinkin; blinkin, bub-linking kinetochore protein; Bub-linking kinetochore protein; cancer susceptibility candidate 5; cancer susceptibility candidate gene 5 protein; cancer/testis antigen 29; CASC5; CT29; D40; hKNL-1; hSpc105; kinetochore null 1 homolog; kinetochore scaffold 1; kinetochore-null protein 1; MCPH4; microcephaly, primary autosomal recessive 4; PPP1R55; Protein CASC5; Protein D40/AF15q14; protein phosphatase 1, regulatory subunit 55; Spc7
Applications