Rabbit anti-CHD3 IHC Antibody Affinity Purified
Catalog #
CHD3
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 1600 and 1650
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
Guinea Pig,
Horse,
Dog,
Pig,
Rabbit,
Monkey,
Rat
Horse,
Dog,
Pig,
Rabbit,
Monkey,
Rat
Dog,
Pig,
Rabbit,
Monkey,
Rat
Pig,
Rabbit,
Monkey,
Rat
Rabbit,
Monkey,
Rat
Monkey,
Rat
Rat
Human
2 - 8 °C
1 year from date of receipt
USA
CHD3 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD3 is a key component of the NuRD (nucleosomal remodeling) complex and directly interacts with histone deacetylases 1 and 2, ATR, and TRIM 27. Studies in several species suggest a role for CHD3 in the repression of developmental genes.
Chromodomain-helicase-DNA-binding protein 3
Alternate Names
ATP-dependent helicase CHD3; CHD-3; chromodomain-helicase-DNA-binding protein 3; hZFH; mi-2 autoantigen 240 kDa protein; Mi-2a; Mi2-ALPHA; ZFH; zinc finger helicase; zinc-finger helicase (Snf2-like)
Applications