/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-Dab2 Antibody
NEW!
Primary Antibodies  

Rabbit anti-Dab2 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

Dab2

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 275 and 325

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


Request Formulation Change
Additional Product Information

Disabled homolog 2 (Dab2) is an adapter protein that functions as a clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Dab2 can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containing non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P98082].

1601

DAB2

DAB2, clathrin adaptor protein

P98082

Disabled homolog 2

Alternate Names

adaptor molecule disabled-2; Dab, mitogen-responsive phosphoprotein, homolog 2; differentially expressed in ovarian carcinoma 2; differentially-expressed protein 2; disabled homolog 2; disabled homolog 2, mitogen-responsive phosphoprotein; DOC2; DOC-2

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.