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Rabbit anti-DCPS Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
DCPS
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1 and 50
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

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Product Details

Specifications
Verified Reactivity
Human
Antigen Species
Human
Stock Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to DCPS immobilized on solid support.

The epitope recognized by A305-426A-T maps to a region between residue 1 to 50 of human Scavenger mRNA-decapping enzyme DcpS using the numbering given in entry Q96C86.2 (GeneID 28960).

Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

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Gene & Protein Information

DCPS is a decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. DCPS Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP)[taken from NCBI Entrez Gene (Gene ID: 28960)].

28960

DCPS

decapping enzyme, scavenger

Q96C86

m7GpppX diphosphatase

Alternate Names

5'-(N(7)-methyl 5'-triphosphoguanosine)-mRNA diphosphatase, ARS, DCS1, DCS-1, decapping scavenger enzyme, epididymis secretory sperm binding protein, heat shock-like protein 1, HINT5, HINT-5, hint-related 7meGMP-directed hydrolase, histidine triad nucleotide-binding protein 5, histidine triad protein member 5, homolog of C. elegans 7meGMP-directed hydrolase dcs-1, HSL1, HSPC015, m7GpppX diphosphatase, mRNA decapping enzyme, scavenger mRNA-decapping enzyme DcpS

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-12% SDS-PAGE.