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Rabbit anti-DOCK2 Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
DOCK2
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 550 and 600
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$131.00 $464.00
Qty:

Product Details

Specifications

Verified Reactivity
Human
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Production Procedures
Antibody was affinity purified using an epitope specific to DOCK2 immobilized on solid support.

The epitope recognized by A305-399A-T maps to a region between residue 550 to 600 of human using the numbering given in entry Q92608.2 (GeneID 1794).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to DOCK2 immobilized on solid support.

The epitope recognized by A305-399A maps to a region between residue 550 to 600 of human using the numbering given in entry Q92608.2 (GeneID 1794).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Country of Origin
USA

Additional Product Information

Dedicator of cytokinesis protein 2 (DOCK2) is Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. DOCK2 activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. DOCK2 may also participate in IL2 transcriptional activation via the activation of RAC2 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q92608].

1794
DOCK2
dedicator of cytokinesis 2
Q92608
Dedicator of cytokinesis protein 2

Alternate Names

dedicator of cyto-kinesis 2; dedicator of cytokinesis protein 2; IMD40

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.