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Rabbit anti-eIF4G1/eIF4GI Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
eIF4G1/eIF4GI
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 200 and 250
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (200 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

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Product Details

Specifications
Verified Reactivity
Human
Antigen Species
Human
Stock Concentration
40 µg/ml
200 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to eIF4G1/eIF4GI immobilized on solid support.

The epitope recognized by A301-774A-T maps to a region between residue 200 and 250 of human eukaryotic translation initiation factor 4 gamma, 1 using the numbering given in entry NP_886553.2 (GeneID 1981).

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Gene & Protein Information

Eukaryotic initiation factor 4 gamma 1 (eIF4G1) is one of 2 eIF4G proteins found in human (eIF4G1 and eIF4G3). eIF4G is a subunit of the eIF4F heterotrimeric complex composed of eIF4A, eIF4E, and eIF4G. eIF4F plays a role in recruiting the ribosome to the 5’-end of capped mRNAs during protein synthesis. In the eIF4F complex, eIF4G functions as a scaffold to bridge the cap-binding subunit, eIF4E, with the RNA helicase, eIF4A.

1981

EIF4G1

eukaryotic translation initiation factor 4 gamma 1

Q04637

Eukaryotic translation initiation factor 4 gamma 1

Alternate Names

EIF4F, EIF4G, eIF-4G 1, EIF-4G1, EIF4-gamma, eIF-4-gamma 1, EIF4GI, eucaryotic translation initiation factor 4G, eukaryotic translation initiation factor 4 gamma 1, P220, PARK18

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.

Citations (1)