Rabbit anti-GEMIN2 Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
GEMIN2 found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. GEMIN2 interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex [taken from NCBI Entrez Gene (Gene ID: 8487)].
Alternate Names
component of gems 2; gem-associated protein 2; gemin-2; SIP1; SIP1-delta; SMN interacting protein 1-delta; SMN-interacting protein 1; survival of motor neuron protein interacting protein 1; Survival of motor neuron protein-interacting protein 1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.