Rabbit anti-Gigaxonin Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Gigaxonin is a probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. It is also a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins such as TBCB, MAP1B, and MAP1S and is critical for neuronal maintenance and survival [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9H2C0].
Alternate Names
epididymis secretory sperm binding protein; GAN1; gigaxonin; kelch-like family member 16; kelch-like protein 16; KLHL16
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.