Rabbit anti-GSDMD Antibody Affinity Purified

Product Details
Specifications
The epitope recognized by A305-735A maps to a region between residue 225 to 275 of human Gasdermin-D using the numbering given in entry P57764.1 (GeneID 79792).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to GSDMD immobilized on solid support.
The epitope recognized by A305-735A-T maps to a region between residue 225 to 275 of human Gasdermin-D using the numbering given in entry P57764.1 (GeneID 79792).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor [taken from NCBI Entrez Gene (Gene ID: 79792)].
Alternate Names
DF5L; DFNA5L; FKSG10; gasdermin domain containing 1; gasdermin domain-containing protein 1; gasdermin-D; GSDMDC1
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.