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Rabbit anti-GSDMD Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
GSDMD
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 225 and 275
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$131.00 $464.00
Qty:

Product Details

Specifications

Verified Reactivity
Human
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Production Procedures
Antibody was affinity purified using an epitope specific to GSDMD immobilized on solid support.

The epitope recognized by A305-735A maps to a region between residue 225 to 275 of human Gasdermin-D using the numbering given in entry P57764.1 (GeneID 79792).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to GSDMD immobilized on solid support.

The epitope recognized by A305-735A-T maps to a region between residue 225 to 275 of human Gasdermin-D using the numbering given in entry P57764.1 (GeneID 79792).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Country of Origin
USA

Additional Product Information

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor [taken from NCBI Entrez Gene (Gene ID: 79792)].

79792
GSDMD
gasdermin D
P57764
Gasdermin-D

Alternate Names

DF5L; DFNA5L; FKSG10; gasdermin domain containing 1; gasdermin domain-containing protein 1; gasdermin-D; GSDMDC1

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.