Bethyl Laboratories
Rabbit anti-Histone H4 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00098
TargetHistone H4
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
Histone H4 is one of four histone proteins that assemble into an octamer to form the nucleosome core and serve to spool and compact DNA into chromatin. Histones are subject to a complex set of post-translational modifications (acetylation, methylation, phosphorylation, ubiquitination, sumoylation, citrullination, and ADP ribosylation) that are important to the regulation of gene transcription, DNA replication, and DNA repair.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 53 and C-terminus
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetHistone H4
Antigen Species
Human
Gene ID121504
Gene Symbol
HIST4H4
Gene Name
histone cluster 4 H4
Uniprot IDP62805
Protein Name
Histone H4
Alternate Names
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to Histone H4 immobilized on solid support.
The epitope recognized by IHC-00098 maps to a region between residue 50 and the C-terminus (residue 103) of human Histone H4 using the numbering given in entry NP_778224.1 (GeneID 121504).
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00098Open
Product DatasheetPDF · IHC-00098 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00098 · Lot 1 (current lot)Open
Services
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