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Rabbit anti-IMMT/Mitofilin Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
IMMT/Mitofilin
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 100 and 150
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

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Product Details

Specifications
Verified Reactivity
Human
Antigen Species
Human
Stock Concentration
100 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to IMMT/Mitofilin immobilized on solid support.

The epitope recognized by A305-023A-T maps to a region between residue 100 to 150 of human Mitochondrial inner membrane protein using the numbering given in entry Q16891.1 (GeneID 10989).

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Gene & Protein Information

Mitofilin is a component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Mitofilin plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology [taken from NCBI Entrez Gene (Gene ID: 10989)].

10989

IMMT

inner membrane mitochondrial protein

Q16891

MICOS complex subunit MIC60

Alternate Names

cell proliferation-inducing gene 4/52 protein, cell proliferation-inducing protein 52, heart muscle protein, HMP, Mic60, MICOS complex subunit MIC60, MINOS2, mitochondrial inner membrane organizing system 2, mitochondrial inner membrane protein, mitofilin, motor protein, P87, P87/89, P89, PIG4, PIG52, proliferation-inducing gene 4

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.