Rabbit anti-INCENP IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00060 maps to a region between residue 325 and 400 of human Inner Centromere Protein using the numbering given in entry Q9NQS7 (GeneID 3619). Antibody was affinity purified using an epitope specific to INCENP immobilized on solid support.
The epitope recognized by IHC-00060-T maps to a region between residue 325 and 400 of human Inner Centromere Protein using the numbering given in entry Q9NQS7 (GeneID 3619).
Additional Product Information
INCENP (inner centromere protein) is a component of the chromosomal passenger complex (CPC) which is a group of proteins that localizes to the centromere during specific stages of the cell cycle. The CPC is key regulator of mitosis that functions in spindle assembly, chromosome alignment, and segregation. INCENP contains a coiled-coil domain that interacts with microtubules and is required for the spindle-assembly checkpoint.
Alternate Names
binds and activates aurora-B and -C in vivo and in vitro; chromosomal passenger protein; inner centromere protein; inner centromere protein antigens 135/155kDa; inner centromere protein INCENP
Applications
Formaldehyde-Fixed Cells 1:100 - 1:500:
Permeabilization with Triton-X 100 is recommended.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.