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Rabbit anti-ITGB4/CD104/Integrin beta-4 Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
ITGB4/CD104/Integrin beta-4
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1772 and 1822
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Human
Presumed Reactivity
Rat, Mouse
Antigen Species
Human
Stock Concentration
100 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to ITGB4 immobilized on solid support.

The epitope recognized by A305-203A-T maps to a region between residue 1772 to 1822 of human Integrin beta-4 using the numbering given in entry P16144.5 (GeneID 3691).

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Gene & Protein Information

The gene ITGB4, also known as CD104, encodes for the integrin beta subunit integrin beta-4. Integrin alpha-6/beta-4 is a receptor for laminin and plays a critical structural role in the hemidesmosome of epithelial cells. ITGA6:ITGB4 is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in ITGB4/CD104 are associated with epidermolysis bullosa with pyloric atresia [taken from NCBI Entrez Gene (Gene ID: 3691) and UniProtKB (Entry: P16144)].

3691

ITGB4

integrin subunit beta 4

P16144

Integrin beta-4

Alternate Names

CD antigen CD104, CD104, CD104 antigen, GP150, integrin beta-4

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.