Rabbit anti-Junctophilin-2 Antibody
Catalog #
Junctophilin-2
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 625 and 675
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
2 - 8 °C
1 year from date of receipt
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Junctophilins provide a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. Junctophilin-2 is necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release, and contributes to the construction of skeletal muscle triad junctions [Taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BR39].
Alternate Names
