Rabbit anti-KIF14 Antibody Affinity Purified
Catalog #
KIF14
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 50 and 100
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
USA
The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF14 silencing experiments suggest that KIF14 plays a multi-functional role in mitosis and cytokinesis. KIF14 has also been identified as a candidate oncogene whose overexpression may lead to genomic instability and act as a reporter of poor-prognosis in breast cancer.
Alternate Names
epididymis secretory sperm binding protein; kinesin-like protein KIF14; MCPH20; MKS12
Applications