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Rabbit anti-KIF20A/RAB6KIFL Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
KIF20A/RAB6KIFL
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 840 and C-term
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

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Product Details

Specifications
Verified Reactivity
Human
Presumed Reactivity
Bovine
Antigen Species
Human
Stock Concentration
100 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to KIF20A/RAB6KIFL immobilized on solid support.

The epitope recognized by A300-879A-T maps to a region between residue 840 and the C-terminus (residue 890) of human Kinesin Family Member 20A (RAB6 Interacting, Kinesin-Like) using the numbering given in entry NP_005724.1 (GeneID 10112).

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Gene & Protein Information

The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF20A/RAB6KIFL plays a role in transport within the golgi via interaction with Rab6 small GTPase as well as in mitosis and cytokinesis where it localizes to the spindle in anaphase and cleavage furrow and midbody in telophase.

10112

KIF20A

kinesin family member 20A

O95235

Kinesin-like protein KIF20A

Alternate Names

GG10_2, kinesin-like protein KIF20A, mitotic kinesin-like protein 2, MKLP2, RAB6 interacting, kinesin-like (rabkinesin6), rab6-interacting kinesin-like protein, RAB6KIFL, rabkinesin-6

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.

Citations (7)