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Rabbit anti-MADD IHC Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

MADD

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 1597 and C-terminus

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

$121.00 $459.00
Qty:

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Guinea Pig,

Mouse,

Horse,

Dog,

Bovine,

Monkey,

Rat

Antigen Species

Human

Concentration
100 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Production Procedures

Antibody was affinity purified using an epitope specific to MADD immobilized on solid support.

The epitope recognized by IHC-00621 maps to a region between residue 1597 and 1647 of human MAP-kinase activating death domain using the numbering given in entry NP_003673.3 (GeneID 8567).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Antibody was affinity purified using an epitope specific to MADD immobilized on solid support.

The epitope recognized by IHC-00621-T maps to a region between residue 1597 and 1647 of human MAP-kinase activating death domain using the numbering given in entry NP_003673.3 (GeneID 8567).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Country of Origin

USA

Additional Product Information

MAP kinase-activating death domain protein (MADD) is a death domain containing protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activate protein kinase (MAPK) and transduce apoptotic signals. MADD is a multi-pass membrane protein that exists as multiple alternatively spliced forms.

8567

MADD

MAP kinase activating death domain

Q8WXG6

MAP kinase-activating death domain protein

Alternate Names

DENN; differentially expressed in normal and neoplastic cells; IG20; insulinoma glucagonoma clone 20; MAP kinase-activating death domain protein; Rab3 GDP/GTP exchange factor; RAB3GEP

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.