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Rabbit anti-MAP1A Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
MAP1A
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 2050 and 2100
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

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Product Details

Specifications
Verified Reactivity
Human
Antigen Species
Human
Stock Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to MAP1A immobilized on solid support.

The epitope recognized by A301-445A-T maps to a region between residue 2050 and 2100 of human microtubule-associated protein 1A using the numbering given in entry NP_002364.5 (GeneID 4130).

Immunoglobulin concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.

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Gene & Protein Information

MAP1A is one of the founding members of the MAP (microtubule-associated protein) family of proteins involved in microtubule assembly. MAP1A is almost exclusively expressed in the mature brain and is important to dendrite formation. MAP1A is processed by proteolytic cleavage that leads to the generation of a MAP1A heavy chain of 350 kDa and a LC2 light chain of 28 kDa. Both the heavy and light chain have been shown to bind microtubules as well as a number of other proteins that play a role in synapse formation.

4130

MAP1A

microtubule associated protein 1A

P78559

Microtubule-associated protein 1A

Alternate Names

MAP-1A, MAP1L, microtubule-associated protein 1A, MTAP1A, proliferation-related protein p80

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 3-8% SDS-PAGE.