Rabbit anti-MAVS/VISA Antibody
Catalog #
MAVS/VISA
Human
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
between 150 and 200
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Mitochondrial Antiviral-Signaling Protein (MAVS), also known as Virus-Induced Signaling Adaptor (VISA), is an adaptor protein that functions in the activation of the nuclear factor KappaB (NF-kappaB) and interferon regulatory factor 3 (IRF3) to mediate host innate immune responses against double-stranded RNA viral infection. MAVS (VISA) is localized to the outer mitochondrial membrane. Hepatitis C virus NS3/4A protease cleaves MAVS as part of an immune-evasion strategy.
Mitochondrial antiviral-signaling protein
Alternate Names
CARD adapter inducing interferon beta; CARD adaptor inducing IFN-beta; CARDIF; IFN-B promoter stimulator 1; interferon beta promoter stimulator protein 1; IPS1; IPS-1; MAVS; mitochondrial antiviral-signaling protein; putative NF-kappa-B-activating protein 031N; virus-induced signaling adaptor; virus-induced-signaling adapter; VISA
Applications