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Rabbit anti-NFAT3 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

NFAT3

Reactivity:

Human

,

Mouse

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 300 and 350

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

NFAT3 (nuclear factor of activated T-cells 3) plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. NFAT3 is transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. NFAT3 increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. It may also play an important role in myotube differentiation, cardiac development and hypertrophy, and in deafferentation-induced apoptosis of sensory neurons [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q14934].

4776

NFATC4

nuclear factor of activated T cells 4

Q14934

Nuclear factor of activated T-cells, cytoplasmic 4

Alternate Names

NFAT3; NF-AT3; NFATc4; NF-ATC4; nuclear factor of activated T-cells, cytoplasmic 4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; T-cell transcription factor NFAT3

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.