Rabbit anti-NUPL Antibody Affinity Purified
Catalog #
NUPL
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 512 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Bovine,
Rat
Rat
Human
2 - 8 °C
1 year from date of receipt
USA
NUPL or hRIP (human Rev interacting protein) was originally identified in a yeast two-hybrid screen for proteins that interact with the Rev protein of the human immunodeficiency virus type 1 (HIV-1). Structurally, hRIP contains an ARFGAP (ARF GTPase-activating protein) domain. hRIP was found to have homology with nucleoporins; thus it is also referred to as nucleoporin-like protein (NUPL) RIP. hRIP is essential to HIV-1 replication but not for cell viability, and it appears to be important for the export of HIV-1 RNA from the perinuclear region to the cytoplasm.
Alternate Names
arf-GAP domain and FG repeat-containing protein 1; arf-GAP domain and FG repeats-containing protein 1; HIV-1 Rev-binding protein; HRB; hRIP, Rev interacting protein; nucleoporin-like protein RIP; RAB; Rab, Rev/Rex activation domain-binding protein; rev/Rex activation domain-binding protein; rev-interacting protein; RIP
Applications