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Rabbit anti-OX40/CD134 Recombinant Monoclonal Antibody [BLR042F]

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
OX40/CD134
Reactivity:
Human
Host:
Rabbit
Clonality:
Recombinant Monoclonal
Clone:
BLR042F
Format:
Whole IgG
Immunogen:
residues 29-216 (ECD)
IsoType:
IgG
Purity:
Purified
100 µl (50+ tests)

10 µl (5+ tests)

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Product Details

Specifications
Verified Reactivity
Human
Antigen Species
Human
Stock Concentration
50 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Recombinant antibody was purified from cell culture supernatant.

Immunogen was a recombinant protein representing the extracellular domain of human OX40/CD134 (residues 29-216, NP_003318.1).

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Gene & Protein Information

OX40/CD134 is a member of the TNF-receptor superfamily that has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested OX40/CD134 plays a role in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [taken from NCBI Entrez Gene (Gene ID: 3659)].

7293

TNFRSF4

TNF receptor superfamily member 4

P43489

Tumor necrosis factor receptor superfamily member

Alternate Names

ACT35, ACT35 antigen, ATC35 antigen, CD antigen CD134, CD134, CD134 antigen, IMD16, lymphoid activation antigene ACT35, OX40, OX40 antigen, OX40 cell surface antigen, OX40 homologue, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, tax-transcriptionally activated glycoprotein 1 receptor, tumor necrosis factor receptor superfamily member 4, TXGP1L