Rabbit anti-Oxytocinase Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Oxytocinase is a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] [taken from NCBI Entrez Gene (Gene ID: 4012)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UIQ6].
Alternate Names
angiotensin IV receptor; AT (4) receptor; CAP; cystinyl aminopeptidase; insulin-regulated aminopeptidase; insulin-regulated membrane aminopeptidase; insulin-responsive aminopeptidase; IRAP; leucyl-cystinyl aminopeptidase; otase; oxytocinase; placental leucine aminopeptidase; PLAP; P-LAP; vasopressinase
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.