Bethyl Laboratories® Rabbit anti-PA1 IHC Antibody, Affinity Purified - 100 µl (50+ slides)
Catalog #
PA1
Human
IHC
Rabbit
Polyclonal
Whole IgG
Between 204 and 254
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Horse,
Monkey
Human
2 - 8 °C
1 year from date of receipt
PA1 (PTIP-associated protein 1) was isolated as a protein that associates with PTIP (Pax transactivation domain-interacting protein), a nuclear protein involved in the DNA damage response and interacts with the Pax2 transactivation domain. Along with PTIP, PA1 has been found to be present in a MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase complex. PA1 also appears to be important to the DNA damage response and repair. This involvement in DNA damage signaling is reported to be independent of its MLL association. PA1 has also been identified as GAS (glutamate-rich coactivator interacting with SRC1/NCOA1). As an interactor of SRC1 (steroid receptor coactivator 1), PA1 functions as a transcription cofactor.
PAXIP1-associated glutamate-rich protein 1
Alternate Names
C16orf53; GAS; glutamate-rich coactivator associated with SRC1; glutamate-rich coactivator interacting with SRC1; glutamate-rich coactivator interacting with SRC1/NCOA1; PA1; PAXIP1-associated glutamate-rich protein 1; PAXIP1-associated protein 1; PTIP-associated 1 protein; PTIP-associated protein 1
Applications
