Rabbit anti-Paxillin IHC Antibody Affinity Purified

Product Details
Specifications
The epitope recognized by IHC-00436 maps to a region between residues 1 and 50 of human Paxillin using the numbering given in Swiss-Prot entry P49023 (GeneID 5829). Antibody was affinity purified using an epitope specific to Paxillin immobilized on solid support.
The epitope recognized by IHC-00436-T maps to a region between residues 1 and 50 of human Paxillin using the numbering given in Swiss-Prot entry P49023 (GeneID 5829).
Additional Product Information
Paxillin functions as a signal transduction adaptor protein that localizes to focal adhesions and is involved in cell-adhesion and motility. Paxillin is a substrate of several protein kinases such as Src, FAK, and JNK. Serine and threonine phosphorylation of Paxillin appears to dictate its specific cellular activities.
Alternate Names
paxillin; testicular tissue protein Li 134
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.