Rabbit anti-Pds5B Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Pds5B is a cohesin interacting protein. Cohesin functions to hold sister chromatids together during meiosis and mitosis and ensures proper segregation of chromosomes. Pds5B may play a specific role in the stabilization and destabilization of cohesin-mediated cohesion. Pds5B expression has been demonstrated to be androgen-induced and mediate the androgen-induced proliferative arrest of human prostate cells.
Alternate Names
androgen induced inhibitor of proliferation; androgen-induced proliferation inhibitor; androgen-induced prostate proliferative shutoff-associated protein AS3; androgen-induced shutoff 3; APRIN; AS3; CG008; sister chromatid cohesion protein PDS5 homolog B
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.