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Rabbit anti-Phospho SMC3 (S1083) IHC Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
SMC3 Phospho (S1083)
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Surrounding serine 1083
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (50+ slides)

10 µl (5+ slides)

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Product Details

Specifications
Verified Reactivity
Mouse, Human
Presumed Reactivity
West Indian ocean coelacanth, Duckbill platypus, Ferret, Zebra finch, Turkey, White-tufted-ear marmoset, Crab-eating macaque, Panda, Monkey, African elephant, Pig, Naked mole rat, Rabbit, Small-eared galago, Chinese hamster, Guinea pig_10141, Little brown bat, Gray short-tailed opossum, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Dog, Bovine, Chicken, Orangutan, Horse, Rat
Antigen Species
Human
Stock Concentration
50 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to Phospho SMC3 (S1083) immobilized on solid support.

The epitope recognized by IHC-00070-T maps to a region surrounding residue 1083 when Serine 1083 is phosphorylated of human Structural Maintenance of Chromosomes 3 using the numbering given in SwissProt entry Q9UQE7 (GeneID 9126).

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Gene & Protein Information

SMC3 (structural maintenance of chromosomes 3) is a component of the cohesin complex which is critical for precise duplication and segregation of chromosomes. SMC3 heterodimerizes with SMC1 and associates with two non-SMC subunits, Rad21/Scc1 and Scc3, to form the cohesin complex.

9126

SMC3

structural maintenance of chromosomes 3

Q9UQE7

Structural maintenance of chromosomes protein 3

Alternate Names

BAM, Bamacan, basement membrane-associated chondroitin proteoglycan, BMH, CDLS3, Chondroitin sulfate proteoglycan 6, chondroitin sulfate proteoglycan 6 (bamacan), chromosome-associated polypeptide, CSPG6, HCAP, SMC protein 3, SMC-3, SMC3L1, structural maintenance of chromosomes protein 3

Applications

Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated.