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Rabbit anti-PLK1 IHC Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

PLK1

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 325 and 375

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

$121.00 $459.00
Qty:

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Rabbit

Antigen Species

Human

Concentration
250 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Production Procedures

Antibody was affinity purified using an epitope specific to PLK1 immobilized on solid support.

The epitopes recognized by IHC-00071 maps to a region between residues 325 and 375 of human Polo-like kinase using the numbering given in SwissProt entry P53350 (GeneID 5347).

Antibody was affinity purified using an epitope specific to PLK1 immobilized on solid support.

The epitope recognized by IHC-00071-T maps to a region between residues 325 and 375 of human Polo-like kinase using the numbering given in SwissProt entry P53350 (GeneID 5347).

Country of Origin

USA

Additional Product Information

Polo-like kinase 1 (PLK1) activity is central to the progression through mitosis. PLK1 plays an essential role in spindle formation and chromosome segregation. Recent studies suggest that PLK1 is specifically involved in anaphase spindle elongation, Rho localization to the contractile ring and cytokinesis.

5347

PLK1

polo like kinase 1

P53350

Serine/threonine-protein kinase PLK1

Alternate Names

cell cycle regulated protein kinase; PLK; PLK-1; polo (Drosophia)-like kinase; Polo-like kinase 1; serine/threonine-protein kinase 13; serine/threonine-protein kinase PLK1; STPK13

Applications

Formaldehyde-Fixed Cells 1:100 - 1:500:

Permeabilization with Triton-X 100 is recommended.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.