Rabbit anti-PRDM1/Blimp-1 Recombinant Monoclonal Antibody [BLR247L]
Catalog #
PRDM1/BLIMP-1
Human
WB
Rabbit
Recombinant Monoclonal
BLR247L
Whole IgG
between 350 and 400
IgG
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
PDRM1, aka Blimp-1, is a transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. PDRM1 binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter and acts as a repressor of beta-interferon gene expression. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75626].
Alternate Names
Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP1; BLIMP-1; B-lymphocyte-induced maturation protein 1; Positive regulatory domain I-binding factor 1; PR domain 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PRDI-BF1; PRDI-binding factor 1; PRDI-binding factor-1
Applications
