Rabbit anti-PZR Antibody Affinity Purified

Product Details
Specifications
The epitope recognized by A304-411A maps to a region between residue 225 to 275 of human Protein Zero Related using the numbering given in entry NP_003944.1 (GeneID 9019).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to PZR immobilized on solid support.
The epitope recognized by A304-411A-T maps to a region between residue 225 to 275 of human Protein Zero Related using the numbering given in entry NP_003944.1 (GeneID 9019).
Additional Product Information
Protein zero-related (PZR) is a cell surface receptor involved in signal transduction processes. PZR recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. It is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95297].
Alternate Names
immunoglobulin family transmembrane protein; MPZL1b; myelin protein zero-like protein 1; protein zero related; Protein zero-related; PZR; PZR1b; PZRa; PZRb
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.