Rabbit anti-REST IHC Antibody Affinity Purified

Product Details
Specifications
The epitope recognized by IHC-00141 maps to a region between residues 1050 and the C-terminus (residue 1097) of human RE1-silencing transcription factor using the numbering given in entry NP_005603.2 (GeneID 5978). Antibody was affinity purified using an epitope specific to REST immobilized on solid support.
The epitope recognized by IHC-00141-T maps to a region between residues 1050 and the C-terminus (residue 1097) of human RE1-silencing transcription factor using the numbering given in entry NP_005603.2 (GeneID 5978).
Additional Product Information
RE1-Silencing Transcription Factor (REST) is a transcriptional repressor that silences neuronal gene expression in non-neuronal cells by binding to the neuron-restrictive silencer element (NRSE). REST is a Kruppel-type zinc finger transcription factor that mediates repression through its interaction with the mSin3 and CoREST corepressors and the HDAC1 and HDAC2 histone deacetylases.
Alternate Names
DFNA27; GINGF5; HGF5; neural-restrictive silencer factor; neuron restrictive silencer factor; NRSF; RE1-silencing transcription factor; repressor binding to the X2 box; WT6; X2 box repressor; XBR
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.